Ma Zi Ren Wan - 麻子仁丸 - Hemp-Seed Pill

English:	Hemp Seed Pill
Also Known As:	Cannabis Seed Pill Apricot and Linum Formula Pi Yue Ma Ren Wan

Herbs And Actions

Pharmaceutical Latin	Pin Yin	Dosage	Actions
Sm. Cannabis	Huo Ma Ren	5-30g	Moistens the Intestines and unblocks the bowels. With Xing Ren, Bai Shao and Zhi Shi, for constipation due to Heat induced Dryness in the Stomach and Intestines.
Sm. Armeniacae	Xing Ren	2-10g	Descends Qi, Harmonizes, Moistens Intestines, Unblocks bowels.
Rx. Paeoniae Alba	Bai Shao	2-15g	Nourishes Blood. astringes Yin and harmonizes the Interior.
Fr. Aurantii Immaturus	Zhi Shi	2-10g	Disperses intestinal accumulation, descends Qi and reduces distention. With Hou Po, for Qi Stagnation with distention, swelling and pain. With Da Huang, for Qi Stagnation with constipation and abdominal swelling. With Huo Po and Da Huang, for abdominal distention, pain and fullness from Heat clumping with the stool and constipation with abdominal fullness and pain. With Bai Shao, for Qi and Blood Stagnation with abdominal pain.
Cx. Magnoliae Officinalis	Hou Po	2-10g	Removes fullness and distention, descends Qi and resolves Food Stagnation. With Zhi Shi, for abdominal or chest distention, focal epigastric distention, wheezing, shortness of breath nausea, rebellious Qi or constipation from Cold, Heat, Dampness or Phlegm as long as clumped Qi is at the root of the problem. With Da Huang and Zhi Shi, for constipation due to accumulation and stagnation.
Rx. et Rz. Rhei	Da Huang	4-10g	Purges the Intestines and drains Heat. With Huo Ma Ren and Xing Ren, for moderate constipation and habitual constipation with Deficiency.
(Apis Mel [honey])	(Feng Mi)	(15-30g)	(Moistens the Intestines.)

Formula Actions

• Invigorates Blood
• Dispels Blood Stasis
• Moves Qi
• Lubricates the Intestines
• Moves the bowels
• Purges Heat
• Alleviates pain

Syndromes

• Colon Heat
• Deficiency of Fluid in Colon
• Dry Heat Retention in the Stomach and Intestines due to Jin Ye Deficiency
• Yang Ming Xu
• Constipation due to Intestinal Dryness & Heat → Spleen Bind (Secondary source)

Clinical Manifestations

Constipation with hard, difficult to expel stool Dry skin Hemorrhoids Nocturia Dizziness

Scanty urination Maybe frequent urination T: Pink or Red C: Yellow and dry P: Slippery and rapid or Thready and rapid or Deep and rapid or Superficial and choppy

Treats

Habitual constipation Postpartum constipation Post-surgical constipation Incomplete Intestinal obstruction Reflux gastritis Hemorrhoids Asthma Cystitis Diabetes Dizziness Oliguria Weakness Bad breath Sore throat

Constipation in the weak or elderly Chronic colitis Postoperative ileus Atrophic gastritis Post-hemorrhoidectomy bleeding Cardiopulmonary disease Coronary Heart disease Drug induced constipation Constipation due to atrophic Kidneys Irritable bowel syndrome Vertigo Interstitial cystitis Dry skin

Contraindications And Herb/Drug Interactions

Notes

• Composition: Huo Ma Ren 20g, Xing Ren 10g, Bai Shao 9g, Da Huang 12g, Hou Po 9g, Zhi Shi 9g (Secondary source)
• Compared with Run Chang Wan: Ma Zi Ren Wan treats Fluid deficiency with Dry-Heat in the Stomach and Large Intestine (Spleen Bind, Pi Yue); Run Chang Wan treats Blood deficiency (Desiccated Intestines, Chang Ku).
• Compared with Ji Chuan Jian: Ma Zi Ren Wan treats constipation from Large Intestine Dryness and Heat; Ji Chuan Jian treats constipation from Yang deficiency.

Modifications

For severe depletion of Fluids:		For severe Heat Stagnation with a yellow tongue coat and a rapid pulse:
+ Sm. Platycladi	Bai Zi Ren	+ More Rx. et Rz. Rhei	Da Huang
+ Sm. Trichosanthis	Gua Lou Ren	+ Natrii Sulfas	Mang Xiao
For severe weakness:		For hemorrhoids:
- Rx. et Rz. Rhei	Da Huang	+ Sm. Persicae	Tao Ren
+ Fol. Sennae (small amount)	Fan Xie Ye	+ Rx. Angelicae Sinensis	Dang Gui
For Middle Jiao Qi Deficiency:		For bleeding hemorrhoids:
+ Tonify the Middle and Augment Qi Decoction Bu Zhong Yi Qi Tang		+ Flos Sophorae	Huai Hua Mi
For parasites blocking the Intestines:		+ Rx. Sanguisorbae	Di Yu
+ Fr. Mume	Wu Mei	Or
+ Sm. Arecae	Bing Lang	+ Flos Sophorae	Huai Hua Mi
+ Per. Citri Reticulatae	Chen Pi	+ Rx. Sanguisorbae	Di Yu
For hemorrhoids with constipation:		Cacumen Platycladi	Ce Bai Ye
+ Rz. Coptidis	Huang Lian	For thirst and increased water intake due to Stomach Heat:
+ Rz. Cimicifugae	Sheng Ma	+ Gypsum Fibrosum	Shi Gao
+ Sm. Persicae	Tao Ren	+ Rz. Anemarrhenae	Zhi Mu
+ Rx. Angelicae Sinensis	Dang Gui	For frequent urination:
For habitual constipation with dry stools in geriatric patients:		+ Sm. Euryales	Qian Shi
+ Less Rx. et Rz. Rhei	Da Huang	+ Ootheca Mantidis	Sang Piao Xiao
+ Sm. Platycladi	Bai Zi Ren	+ Fr. Alpiniae Oxyphyllae	Yi Zhi Ren
+ Hb. Cistanches	Rou Cong Rong	For constipation due to Stomach and Intestinal Heat:
+ Rx. Angelicae Sinensis	Dang Gui
For long term constipation due to Stomach and Intestinal Heat:		- Rx. Paeoniae Alba	Bai Shao
- Fr. Aurantii Immaturus	Zhi Shi
- Rx. Paeoniae Alba	Bai Shao	+ Fr. Aurantii	Zhi Ke
- Fr. Aurantii Immaturus	Zhi Shi	+ Sm. Trichosanthis	Gua Lou Ren
+ Fr. Aurantii	Zhi Ke	Or
+ Sm. Trichosanthis	Gua Lou Ren	- Rx. Paeoniae Alba	Bai Shao
- Rx. et Rz. Rhei	Da Huang	- Cx. Magnoliae Officinalis	Hou Po
+ Rx. Ophiopogonis	Mai Men Dong
+ Rx. Asparagi	Tian Men Dong	+ Sm. Trichosanthis	Gua Lou Ren
For constipation due to Stomach and Intestinal Heat with severe Stagnation:		+ Sm. Pruni	Yu Li Ren
+ Rx. Scrophulariae	Xuan Shen
- Rx. Paeoniae Alba	Bai Shao	For severe constipation with hard, dry stools:
- Fr. Aurantii Immaturus	Zhi Shi	+ 15g Natrii Sulfas	Mang Xiao
+ Fr. Aurantii	Zhi Ke	For severe depletion of Fluids with obvious Dryness:
+ Sm. Trichosanthis	Gua Lou Ren
+ Sm. Arecae	Bing Lang	+ 10g Rx. Rehmanniae	Sheng Di Huang
+ Per Citri Reticulatae	Chen Pi	+ 10g Rx. Scrophulariae	Xuan Shen
For constipation with intestinal parasites:		+ 10g Hb. Dendrobii	Shi Hu
+ 15g Sm. Arecae	Bing Lang	For constipation with residual Heat in the Lungs:
For interstitial cystitis:		+ 15g Rx. Scutellariae	Huang Qin
+ Minor Bupleurum Decoction Xiao Chai Hu Tang		+ 15g Sm. Trichosanthis	Gua Lou Ren
For interstitial cystitis with severe constipation:
- Rz. Zingiberis Recens	Sheng Jiang	+ Minor Bupleurum Decoction Xiao Chai Hu Tang
- Rx. et Rz. Rhei	Da Huang
- Rx. Ginseng	Ren Shen	- Rz. Zingiberis Recens	Sheng Jiang
+ 9g Rx. Codonopsis	Dang Shen	- Rx. Ginseng	Ren Shen
For interstitial cystitis without dry stools:		+ 9g Rx. Codonopsis	Dang Shen
+ Minor Bupleurum Decoction Xiao Chai Hu Tang		For interstitial cystitis with marked Qi Deficiency and Dampness:
- Rz. Zingiberis Recens	Sheng Jiang	+ Minor Bupleurum Decoction Xiao Chai Hu Tang
- Rx. Ginseng	Ren Shen
- Sm. Cannabis	Huo Ma Ren	- Rz. Zingiberis Recens	Sheng Jiang
- Sm Armeniacae	Xing Ren	- Rx. et Rz. Rhei	Da Huang
+ 9g Rx. Codonopsis	Dang Shen	- Rx. Ginseng	Ren Shen
+ 9g Rx. Codonopsis	Dang Shen
+ 9g Rz. Atractylodis Macrocephalae	Bai Zhu
+ 9g Poria	Fu Ling